Professor Blair Johnston

Strathclyde Institute of Pharmacy and Biomedical Sciences

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Publications

Quality by digital design to accelerate sustainable medicines development
Mustoe Chantal L, Turner Alice J, Urwin Stephanie J, Houson Ian, Feilden Helen, Markl Daniel, Al Qaraghuli Mohammed M, Chong Magdalene WS, Robertson Murray, Nordon Alison, Johnston Blair F, Brown Cameron J, Robertson John, Adjiman Claire, Batchelor Hannah, Benyahia Brahim, Bresciani Massimo, Burcham Christopher L, Cardona Javier, Cottini Ciro, Dunn Andrew S, Fradet David, Halbert Gavin W, Henson Mark, Hidber Pirmin, Langston Marianne, Lee Ye Seol, Li Wei, Mantanus Jérôme, McGinty John, Mehta Bhavik, Naz Tabbasum, Ottoboni Sara, Prasad Elke, Quist Per-Ola, Reynolds Gavin K, Rielly Chris, Rowland Martin, Schlindwein Walkiria, Schroeder Sven LM, Sefcik Jan, Settanni Ettore, Siddique Humera, Smith Kenneth, Smith Rachel, Srai Jagjit Singh, Thorat Alpana A, Vassileiou Antony, Florence Alastair J
International Journal of Pharmaceutics (2025)
https://doi.org/10.1016/j.ijpharm.2025.125625
Optimisation of additively manufactured coiled flow inverters for continuous viral inactivation processes
Barrera Maria Cecilia, Leech Damien, Josifovic Aleksandar, Tolouei Anita, Alford Gareth, Wallace Martin J, Bennett Nicholas, Wildman Ricky, Irvine Derek J, Croft Anna, Özcan Ender, Florence Alastair J, Johnston Blair, Robertson John, Brown Cameron J
Chemical Engineering Research and Design Vol 213, pp. 126-136 (2025)
https://doi.org/10.1016/j.cherd.2024.11.040
Flexible modelling of the dissolution performance of directly compressed tablets
Maclean Natalie, Armstrong John A, Carroll Mark A, Salehian Mohammad, Mann James, Reynolds Gavin, Johnston Blair, Markl Daniel
International Journal of Pharmaceutics Vol 656 (2024)
https://doi.org/10.1016/j.ijpharm.2024.124084
Deep generative model for pharmaceutical process design
Alvarado. D, Johnston B, Brown C
CMAC Open Days 2023, pp. 56 (2023)
Digital process design to define and deliver pharmaceutical particle attributes
Urwin Stephanie J, Chong Magdalene WS, Li Wei, McGinty John, Mehta Bhavik, Ottoboni Sara, Pathan Momina, Prasad Elke, Robertson Murray, McGowan Mark, al-Attili Mais, Gramadnikova Ekaterina, Siddique Mariam, Houson Ian, Feilden Helen, Benyahia Brahim, Brown Cameron J, Halbert Gavin W, Johnston Blair, Nordon Alison, Price Chris J, Reilly Chris D, Sefcik Jan, Florence Alastair J
Chemical Engineering Research and Design Vol 196, pp. 726-749 (2023)
https://doi.org/10.1016/j.cherd.2023.07.003
A unified ML framework for solubility prediction across organic solvents
Vassileiou Antony D, Robertson Murray N, Wareham Bruce G, Soundaranathan Mithushan, Ottoboni Sara, Florence Alastair J, Hartwig Thoralf, Johnston Blair F
Digital Discovery Vol 2, pp. 356-367 (2023)
https://doi.org/10.1039/D2DD00024E

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Research Interests

Dr Blair Johnston is a Reader in Computational Modelling at the Strathclyde Institute of Pharmacy and Biomedical Sciences. He teaches on the Masters of Pharmacy, Pharmaceutical Analysis, Clinical Pharmacy and Chemistry with Drug Discovery degrees.

My group has research interests in five broad areas: drug discovery, molecular structure simulation, machine learning and prediction, data analysis, and web-enabled science and collaboration tools. In the vast majority of our research, we work closely with experimental scientists in the design and execution of collaborative research to realise the full potential of their laboratory data. This combination of experiment and theory often provides unique insight into the systems being studied.

Professional Activities

Data Mining Crystallisation Kinetics
Contributor
31/3/2021
Novel off-target effects of doxorubicin on cardiovascular gap-junctional proteins
Contributor
5/2/2021
P011 - Endothelial connexin-43 dysregulation in response to the anthracycline doxorubicin
Contributor
14/12/2020
P2.5.6 - Novel off-target effects of anti-cancer drugs on cardiovascular gap-junctional proteins
Contributor
12/10/2020
Data Mining Crystallisation Kinetics
Contributor
19/8/2020
Cambridge Crystallographic Data Centre (CCDC) European UGM and Science Day
Participant
13/6/2019

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Projects

DPN-MED: Digital Plug-and-Produce Network for Sustainable Medicines Development and Manufacturing
Fitzpatrick, Stephen (Principal Investigator) Florence, Alastair (Principal Investigator) Florence, Alastair (Co-investigator) Johnston, Blair (Co-investigator) Markl, Daniel (Co-investigator)
01-Jan-2025 - 30-Jan-2025
PharmaCrystNet: Improving the Predictive Capabilities of Crystallisation Models in
Brown, Cameron (Principal Investigator) Dolean Maini, Victorita (Co-investigator) Johnston, Blair (Co-investigator)
01-Jan-2024 - 31-Jan-2025
SHARPEN: SHARing data to accelerate Pharmaceutical manufacturing Efficiency across trusted Networks
Johnston, Blair (Principal Investigator) Florence, Alastair (Co-investigator) Markl, Daniel (Co-investigator)
01-Jan-2024 - 31-Jan-2026
A Regulatory Science Network for the Digital Transformation of Medicines Development and Manufacturing (10113547)
Markl, Daniel (Principal Investigator) Florence, Alastair (Co-investigator) Johnston, Blair (Co-investigator)
01-Jan-2024 - 31-Jan-2024
DTP 2224 University of Strathclyde | Clark, Connor
Florence, Alastair (Principal Investigator) Johnston, Blair (Co-investigator) Clark, Connor (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
DTP 2224 University of Strathclyde | Robertson, Jason
Johnston, Blair (Principal Investigator) Markl, Daniel (Co-investigator) Robertson, Jason (Research Co-investigator)
01-Jan-2023 - 01-Jan-2029

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Contact

Professor Blair Johnston
Strathclyde Institute of Pharmacy and Biomedical Sciences

Email: blair.johnston@strath.ac.uk
Tel: 548 5756